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Idiopathic pulmonary arterial hypertension

3 associated genes
No signs/symptoms info

PROTEIN INTERACTIONS: 2

Brachydactyly type C

1 OMIM reference -
2 associated genes
11 signs/symptoms

Idiopathic pulmonary arterial hypertension

Brachydactyly type C

BMPR2	(UniProt - OMIM)		BMPR1B	(UniProt - OMIM)
CBLN2	(UniProt - OMIM)		GDF5	(UniProt - OMIM)
KCNK3	(UniProt - OMIM)


INTERACTOME ASSOCIATIONS (click on a score value to see the evidence)	BMPR2 BMPR2	(0.88) (0.85)	GDF5 BMPR1B

Citations in the biomedical literature:

Idiopathic pulmonary arterial hypertension		Brachydactyly type C
	Synonym(s): - IPAH		Synonym(s): (no synonyms)

	Classification (Orphanet): - Rare genetic disease - Rare respiratory disease		Classification (Orphanet): - Rare bone disease - Rare developmental defect during embryogenesis - Rare genetic disease

	Classification (ICD10): - Diseases of the circulatory system -		Classification (ICD10): - Congenital malformations, deformations and chromosomal abnormalities -

	Epidemiological data: Class of prevalence: 1-9 / 1 000 000 Average age onset: variable Average age of death: adult Type of inheritance: sporadic		Epidemiological data: Class of prevalence: unknown Average age onset: neonatal/infancy Average age of death: - Type of inheritance: autosomal dominant

	External references: No OMIM references No MeSH references		External references: 1 OMIM reference - 1 MeSH reference: C537093

Brachydactyly type C
	Very frequent - Autosomal dominant inheritance - Metacarpal anomalies / Archibald's sign - Short hand / brachydactyly - Ulnar deviation of fingers Frequent - Cone epiphyses / epiphysis - Short foot / brachydactyly of toes - Thin / hypoplastic / hyperconvex fingernails Occasional - Clinodactyly of fifth finger - Short stature / dwarfism / nanism - Symphalangy of fingers - Talipes-valgus
Idiopathic pulmonary arterial hypertension
(no data available)